The National Cancer Institute (NCI) has a large repository of small molecules that can be ordered for testing in experimental assays. Remarkably, in hopes of spurring drug discovery the NCI makes these compounds available for free. Researchers need only pay for shipping.
These molecules are ideal for virtual screening, since any potential leads can be ordered cheaply for subsequent experimental validation. I use the NCI compounds often enough that I created this video to show experimentalist collaborators how to order the compounds. Thought I’d post it in case it’s helpful for others as well.
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